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Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease II: Clinical Manifestations01:24

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Chronic Kidney Disease IV: Nursing Management01:18

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Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
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Continuous Renal Replacement Therapy01:30

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
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Progressive Resistance Exercise Training in CKD: A Feasibility Study.

Emma L Watson1, Neil J Greening2, João L Viana3

  • 1Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|December 24, 2014
PubMed
Summary
This summary is machine-generated.

Progressive resistance exercise is feasible and beneficial for patients with chronic kidney disease (CKD), improving muscle size, strength, and exercise capacity. However, recruitment challenges suggest supervised outpatient programs may not be the most practical approach for this population.

Keywords:
Chronic kidney disease (CKD)exercise trainingfeasibilityfunctional capacitymuscle massphysical functioningresistance exerciseskeletal muscle wastingstrength

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Area of Science:

  • Nephrology
  • Exercise Physiology
  • Muscle Biology

Background:

  • Skeletal muscle wasting is a significant complication in chronic kidney disease (CKD), contributing to poor patient outcomes.
  • While resistance exercise promotes muscle hypertrophy in healthy individuals, its effects and feasibility in CKD patients remain under-investigated.

Purpose of the Study:

  • To assess the feasibility of a supervised, progressive resistance exercise program in patients with CKD stages 3b-4.
  • To evaluate the program's impact on muscle size, strength, and physical functioning in this patient group.

Main Methods:

  • A parallel randomized controlled feasibility study was conducted.
  • Patients (CKD stages 3b-4) were assigned to either an 8-week progressive resistance exercise program or a non-exercise control group.
  • Muscle characteristics, strength, and exercise capacity were measured using ultrasonography, dynamometry, and shuttle walk tests.

Main Results:

  • The study enrolled 38 patients, with 87% completing the program; adherence to exercise sessions was high (92%).
  • Progressive resistance exercise significantly increased muscle cross-sectional area, muscle volume, knee extensor strength, and exercise capacity.
  • No significant changes were observed in the control group.

Conclusions:

  • Supervised progressive resistance exercise is well-tolerated by CKD patients and offers clinical benefits.
  • Low recruitment rates indicate that supervised outpatient programs may not be the optimal implementation strategy for this population.