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Breastfeeding is protective to diabetes risk in young adults: a longitudinal study
Abdullah Al Mamun1, Michael J O'Callaghan2, Gail M Williams3
1School of Population Health, University of Queensland, Herston Rd, Herston, Brisbane, QLD, 4006, Australia. mamun@sph.uq.edu.au.
Insights
Breastfeeding for at least 4 months significantly reduces the risk of developing type 2 diabetes in young adults. This protective effect against diabetes is independent of body mass index (BMI).
Area of Science:
- Epidemiology
- Public Health
- Pediatrics
Background:
- The relationship between breastfeeding duration and the long-term risk of diabetes in offspring remains unclear.
- Understanding protective factors for adult-onset diabetes is crucial for public health initiatives.
Purpose of the Study:
- To investigate the association between the duration of breastfeeding and the development of type 2 diabetes in adulthood.
- To determine if breastfeeding offers protection against diabetes independent of other risk factors.
Main Methods:
- A cohort of 3,595 offspring born in Brisbane, Australia (1981-1983) was followed until age 21.
- Maternal-reported breastfeeding duration (never, <4 months, ≥4 months) and offspring diabetes diagnosis were recorded.
- Multiple logistic regression analysis was employed to assess the independent effects of breastfeeding duration on diabetes risk.
Main Results:
- 1.25% of offspring developed diabetes by age 21.
- Offspring breastfed for ≥4 months had a significantly lower odds of developing diabetes (OR 0.29; 95% CI 0.13, 0.63) compared to never-breastfed offspring.
- The protective association remained significant after adjusting for maternal and offspring factors, including BMI.
Conclusions:
- Breastfeeding for a minimum of 4 months provides substantial protection against type 2 diabetes in young adulthood.
- Promoting extended breastfeeding may be a viable strategy for diabetes prevention.
- The protective effect of breastfeeding on diabetes risk is independent of offspring's BMI at age 21.
Aim:
It is unclear whether any breastfeeding or a certain duration of breastfeeding is protective against the development of diabetes in adult offspring.
Methods:
We followed a sub-sample of 3,595 offspring born in the Mater Hospital in Brisbane, Australia between 1981 and 1983 and for whom we had doctor diagnosed self-reported diabetes at age 21 years and maternal reported duration of breastfeeding at 6-month post-natal follow-up. Multiple logistic regression was used to examine the independent associations of duration of breastfeeding (never breastfeed, breastfed <4 months and breastfed ≥4 months) with offspring diabetes by age 21 years.
Results:
Of 3,595 young adults, 45 (1.25 %) developed diabetes by age 21 years. The odds ratio of experiencing diabetes was 0.58 (95 % CI 0.29, 1.16) for offspring who were breastfed <4 months, and it was 0.29 (95 % CI 0.13, 0.63), for offspring who were breastfed at least 4 months compared to the never breastfed offspring. Adjusting for potential confounding and mediating factors including maternal age, education, pre-pregnancy body mass index (BMI), smoking, offspring sports, TV and their BMI at 21 years did not substantially alter this association.
Conclusions:
Findings of this study suggest that infants who are breastfed for longer than 4 months have a substantial protective effect against the development of diabetes in young adulthood, which is independent of current BMI. Promoting breastfeeding for a minimum of 4 months may be a useful strategy for the prevention of diabetes among young adults.
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