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Published on: April 20, 2018
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[Adherence to oral antineoplastic therapy]
R Olivera-Fernandez1, F Fernandez-Ribeiro1, G Piñeiro-Corrales2
1Servicio de Farmacia. Complejo Hospitalario Universitario de Pontevedra.. rosario.olivera.fernandez@sergas.es.
Summary
Most patients adhere to oral chemotherapy, but 28% experience non-adherence, influenced by time from diagnosis and side effects. Improving pharmaceutical care can enhance patient adherence and manage adverse events.
Area of Science:
- Oncology
- Pharmacology
- Patient Adherence Research
Background:
- Oral chemotherapy offers advantages over intravenous administration, including cost and patient comfort.
- Challenges with oral chemotherapy include ensuring patient adherence and monitoring adverse effects.
- Effective management of oral chemotherapy requires understanding adherence patterns.
Purpose of the Study:
- To evaluate real-world adherence rates for oral chemotherapy agents.
- To identify patient and treatment factors influencing adherence.
- To explore opportunities for enhancing pharmaceutical care and patient outcomes.
Main Methods:
- Prospective, observational study conducted over four months.
- Data collected via medical prescriptions, patient history, and interviews.
- Focus on patients receiving oral chemotherapy in an outpatient setting.
Main Results:
- 141 patients were assessed, with 72% demonstrating full adherence.
- 28% of patients reported some level of non-adherence.
- Adherence was significantly influenced by time since diagnosis and the presence of adverse effects.
Conclusions:
- A 72% adherence rate was observed for oral chemotherapy.
- Identified opportunities exist to improve pharmaceutical care.
- Interventions should focus on preventing adverse effects and enhancing patient adherence.
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