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Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
Published on: May 23, 2025
[Antiphosphatidylethanolamine antibody as a marker of antiphospholipid syndrome?]
Cécile Marie Yelnik1, Sylvain Dubucquoi2, Véronique Houfflin-Debarge3
1CHRU de Lille, hôpital Huriez, service de médecine interne et d'explorations vasculaires, 59037 Lille cedex, France.
Abstract:
Antibody to phosphatidylethanolamine (aPE) are observed in thrombotic or obstetric manifestations suggestive of antiphospholipid syndrome (APS). aPE seem to be markers of thrombotic risk independent of conventional antiphospholipid antibodies (aPL). aPE assays are not standardized. There is no therapeutic recommendation for isolated aPE patients with thrombotic or obstetric events. Prospective studies have to be carried to better define the therapeutic management of these patients. Value of aPE in APS criteria is still not established.
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