SENSORIMOTOR DEVELOPMENT IN COCAINE-EXPOSED INFANTS
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Updated: Aug 12, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Robert Arendt1, Lynn Singer1, Jennifer Angelopoulos1
1Case Western Reserve University.
Insights
Prenatal cocaine exposure negatively impacts infant sensorimotor development. Cocaine-exposed infants showed poorer cognitive, motor, and behavioral outcomes at 12 months, independent of other factors.
Area of Science:
- Neuroscience
- Developmental Psychology
- Pediatrics
Background:
- Prenatal exposure to substances like cocaine can impact child development.
- Sensorimotor development is crucial for early childhood milestones.
- Understanding long-term effects requires longitudinal assessment.
Purpose of the Study:
- To investigate the effects of prenatal cocaine exposure on infant sensorimotor development.
- To assess cognitive, motor, and behavioral outcomes at 12 months of age.
- To determine if early motor performance predicts later developmental outcomes.
Main Methods:
- Assessed 167 12-month-olds (74 cocaine-exposed, 93 unexposed) using the Bayley Scales of Infant Development (BSID).
- Utilized Movement Assessment of Infants and Test of Sensory Functions in Infants at 4 months for a subset of infants.
- Controlled for confounding factors in the analysis.
Main Results:
- Cocaine-exposed infants performed significantly worse on the BSID Mental scale at 12 months.
- Cocaine-exposed infants exhibited poorer motor and sensory function at 4 months.
- Early motor performance at 4 months predicted 12-month cognitive, motor, and behavioral outcomes.
- Behavioral outcomes at 12 months were more frequently rated as suspect in the cocaine-exposed group.
Conclusions:
- Prenatal cocaine exposure has a lasting, independent negative effect on infant cognitive, motor, and behavioral development.
- Early sensorimotor assessments can predict later developmental trajectories.
- Intervention strategies may be needed for infants exposed to cocaine prenatally.
Abstract:
This study investigated effects of prenatal cocaine exposure on infant sensorimotor development. One hundred and sixty-seven 12-month-olds (74 cocaine-exposed and 93 unexposed) were assessed using the Bayley Scales of Infant Development (BSID). Ninety-seven had previously been evaluated on the Movement Assessment of Infants and the Test of Sensory Functions in Infants at age 4 months. On the BSID, the cocaine-exposed infants performed less well on the Mental portion and were more frequently rated as behaviorally suspect. Cocaine-exposed infants also performed less well at four months on the motor and sensory measures. Early motor performance predicted 12 month BSID mental, motor and behavioral outcomes. Cocaine exposure had an effect independent from confounders on general cognitive and specific motor and behavioral outcomes.

