Peripapillary serous detachment in multiple evanescent white dot syndrome

Area of Science:

• Ophthalmology
• Retinal Diseases
• Neuro-ophthalmology

Background:

• Multiple evanescent white dot syndrome (MEWDS) is an idiopathic inflammatory condition affecting the outer retina.
• Transient peripapillary serous detachments have not been previously described in MEWDS.

Observation:

• A retrospective case series identified peripapillary serous detachments in four patients with MEWDS.
• Patients presented with characteristic MEWDS symptoms including photopsias and enlarged scotomas.
• Fundus examination revealed chorioretinal white dots and angiographic findings consistent with MEWDS.

Findings:

• All four patients diagnosed with MEWDS exhibited transient peripapillary serous detachments.
• The serous detachments resolved concurrently with the resolution of other MEWDS clinical and fundus findings.
• The condition appears to be self-limited.

Implications:

• Peripapillary serous detachments represent a novel clinical manifestation of MEWDS.
• Recognition of this finding aids in the diagnosis and understanding of MEWDS.
• The self-limited nature of these detachments suggests a favorable prognosis for MEWDS patients.