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Updated: Apr 19, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Hepatocellular carcinoma review: current treatment, and evidence-based medicine
Bulent Karaman1, Bilal Battal1, Sebahattin Sari1
1Bulent Karaman, Bilal Battal, Sebahattin Sari, Samet Verim, Gata Radiology Department, 06291 Ankara, Turkey.
Abstract:
We read with great interest the recent article entitled "Hepatocellular carcinoma review: Current treatment, and evidence-based medicine" by Raza et al, published in World Journal of Gastroenterology. Authors evaluated treatments for early and advanced stage hepatocellular carcinoma based on an extensive review of the relevant literature. They reported that radiofrequency ablation is the most effective local ablative therapy. They concluded that RF ablation is equivalent to surgical resection in well selected patients with early stage hepatocellular carcinoma. In addition, we want to mention microwave ablation besides RF ablation.
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