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Multiple Antimicrobial Resistance of Escherichia coli Isolated from Chickens in Iran

Reza Talebiyan1, Mehdi Kheradmand2, Faham Khamesipour3

  • 1Department of Basis Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Shahrekord Branch, P.O. Box 166, Shahrekord, Iran.

Veterinary Medicine International
|December 31, 2014
PubMed

Insights

Poultry farms show high resistance to common antibiotics in pathogenic E. coli strains. Limiting antimicrobial use is crucial to combat antibiotic resistance in the poultry industry.

Area of Science:

  • Veterinary Microbiology
  • Antimicrobial Resistance

Background:

  • Escherichia coli infections cause significant economic losses in the poultry industry.
  • Antimicrobial agents are widely used to control these infections.

Purpose of the Study:

  • To investigate antimicrobial resistance patterns in pathogenic E. coli (APEC) isolated from broiler chickens.
  • To assess the prevalence of multidrug resistance in APEC strains.

Main Methods:

  • Disc diffusion method was used to test 318 APEC isolates against various veterinary and human antimicrobials.
  • Antibiotic resistance profiles were determined for each isolate.

Main Results:

  • All examined APEC isolates exhibited multiple drug resistance.
  • High resistance rates were observed for Tylosin (88.68%) and Erythromycin (71.70%).
  • Lower resistance was noted for antibiotics less frequently used or exclusively for human medicine.

Conclusions:

  • Multidrug-resistant E. coli is prevalent in diseased broiler chickens in Iran.
  • The findings highlight the risks associated with antimicrobial use in poultry.
  • Restricting antibiotic use in poultry farms is recommended to mitigate resistance development.

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