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Oncologists' experiences with drug shortages.

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Most oncologists experienced cancer drug shortages, with practice structure influencing availability. Veterans Affairs oncologists reported fewer shortages and less use of alternative treatments compared to other practice types.

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Area of Science:

  • Oncology
  • Health Services Research
  • Pharmacology

Background:

  • Injectable cancer drug shortages have been frequently reported over the past decade.
  • Understanding physician experiences is crucial for addressing these supply chain disruptions.

Purpose of the Study:

  • To assess medical oncologist experiences with injectable cancer drug shortages.
  • To identify factors associated with experiencing drug shortages and using less-effective alternatives.

Main Methods:

  • A survey was conducted among medical oncologists treating lung or colorectal cancer patients (2012-2013).
  • Participants reported shortages of specific chemotherapy agents and use of alternatives.
  • Multivariable logistic regression analyzed associations between physician/practice characteristics and shortage experiences.

Main Results:

  • 74% of surveyed oncologists reported experiencing at least one drug shortage.
  • 28% reported using a less-effective alternative drug due to shortages.
  • Veterans Affairs (VA) oncologists were less likely to report shortages or use alternatives compared to single-specialty group practices.

Conclusions:

  • The majority of oncologists face drug shortages, with experiences varying by practice setting.
  • Practice structure, particularly within the VA system, appears to mitigate shortage impact.
  • Further research is needed to quantify patient impact and evaluate management strategies.