Related Experiment Video
Updated: Apr 19, 2026
10:49
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
9.5K
Disease caused by rotavirus infection
Che-Liang Lin1, Shou-Chien Chen2, Shyun-Yeu Liu3
1Internal Medicine Chest Division, Chi-Mei Medical Center, Liouying, Tainan, Taiwan.
The Open Virology Journal
|January 2, 2015
Summary
Rotavirus vaccines effectively reduce childhood diarrheal disease globally. Further research is needed to address remaining challenges in rotavirus gastroenteritis prevention and control.
Area of Science:
- Public Health
- Vaccinology
- Infectious Diseases
Background:
- Rotaviruses are a primary cause of severe diarrheal illness in children worldwide.
- Despite available vaccines, rotavirus remains a significant global health concern.
- Existing rotavirus vaccines demonstrate effectiveness in reducing disease burden.
Purpose of the Study:
- To review the epidemiology of rotaviral gastroenteritis.
- To assess the efficacy and effectiveness of licensed rotavirus vaccines.
- To identify future research directions for rotavirus control.
Main Methods:
- Literature review and synthesis of epidemiological data.
- Analysis of clinical trial and real-world effectiveness studies of rotavirus vaccines.
- Identification of knowledge gaps and research priorities.
Main Results:
- Rotavirus vaccines significantly decrease rotavirus-associated morbidity and mortality.
- Epidemiological patterns of rotavirus infection vary globally.
- Vaccine effectiveness is established, but challenges persist.
Conclusions:
- Licensed rotavirus vaccines are crucial tools for public health.
- Continued surveillance and research are essential for optimizing rotavirus prevention strategies.
- Translational and basic science research is needed to overcome current limitations.
More Related Videos
08:01Author Spotlight: Investigating Viral Disruption of Intestinal Epithelial Signaling – Research Insights and Future Directions
Published on: January 19, 2024
2.1K
11:40Simplified Reverse Genetics Method to Recover Recombinant Rotaviruses Expressing Reporter Proteins
Published on: April 17, 2020
9.6K
Related Concept Videos
01:18Bacterial Gastroenteritis
70
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
70
01:27Cytomegalovirus Disease
71
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
71
01:03Rous Sarcoma Virus (RSV) and Cancer
6.7K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.7K
01:03Rous Sarcoma Virus (RSV) and Cancer
6.2K
6.2K
01:25Cholera
103
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
103
01:18Viral Meningitis
160
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
160