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Related Experiment Video

Updated: Apr 19, 2026

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
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Three-dimensional printing-based electro-millifluidic devices for fabricating multi-compartment particles.

Qiu Lan Chen1, Zhou Liu1, Ho Cheung Shum1

  • 1HKU-Shenzhen Institute of Research and Innovation (HKU-SIRI), Shenzhen, Guangdong 51800, China and Department of Mechanical Engineering, The University of Hong Kong , Haking Wong Building, Pokfulam, Hong Kong.

Biomicrofluidics
|January 2, 2015
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Summary
This summary is machine-generated.

Stereolithographic 3D printing enables fabrication of millifluidic devices for creating multi-compartment particles. This advanced technique allows for precise control over particle structures and encapsulation of various functional ingredients.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Biotechnology

Background:

  • Microfabrication techniques struggle with millimeter-scaled 3D features.
  • Engineering multi-compartment particles is challenging for controlled delivery.
  • Existing methods lack versatility in creating complex particle architectures.

Purpose of the Study:

  • To demonstrate stereolithographic 3D printing for fabricating millifluidic devices.
  • To engineer particles with diverse multi-compartment structures.
  • To showcase the encapsulation of functional materials for various applications.

Main Methods:

  • Utilizing stereolithographic 3D printing to create millimeter-scaled millifluidic networks.
  • Exploiting laminar flow and electric fields for droplet generation and solidification.
  • Fabricating particles with slice-by-slice lamellae, core-shell, and petal structures.

Main Results:

  • Successfully fabricated millifluidic devices capable of producing multi-compartment particles.
  • Demonstrated control over particle structures including lamellar, core-shell, and petal designs.
  • Encapsulated diverse materials like fruit juices, drugs, and magnetic nanoparticles.

Conclusions:

  • Stereolithographic 3D printing offers a robust method for creating complex, compartmentalized particles.
  • The developed electro-millifluidic approach extends the structural possibilities of functional particles.
  • This technology holds promise for applications in food, drug delivery, and bioassays.