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Epigenetic mechanisms in Parkinson's disease

Ya Feng1, Joseph Jankovic2, Yun-Cheng Wu1

  • 1Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China.

Journal of the Neurological Sciences
|January 3, 2015
PubMed
Summary

Epigenetics, changes in gene expression without altering DNA, plays a role in Parkinson's disease (PD) pathogenesis. Understanding these epigenetic modifications may lead to new diagnostic and therapeutic strategies for PD.

Keywords:
DNA methylationEpigenetic modificationHistone acetylationNon-coding RNAsParkinson's disease

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