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Towards personalized compression in mammography: a comparison study between pressure- and force-standardization.
Jerry E de Groot1, Woutjan Branderhorst2, Cornelis A Grimbergen2
1Academic Medical Center, Room L0-151, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; Academic Medical Center, Department of Biomedical Engineering & Physics, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.
Personalized pressure-standardized mammography significantly reduced patient pain compared to conventional force-standardized compression. This new protocol maintained similar average glandular dose and image retake rates, improving the screening experience.
Area of Science:
- Radiology
- Medical Imaging
- Biomedical Engineering
Background:
- Mammography compression aims to reduce breast thickness and improve image quality.
- Conventional force-standardized compression may lead to inconsistent breast thickness and patient discomfort.
- Personalized pressure-standardized compression offers a potentially more effective and comfortable alternative.
Purpose of the Study:
- To compare a conventional force-standardized compression protocol with a personalized pressure-standardized protocol in mammography.
- To evaluate the impact of pressure-standardized compression on breast thickness, patient pain, average glandular dose (AGD), and image retake rates.
Main Methods:
- A novel contact area detector was validated for pressure-standardized compression.
- A double-blinded, intra-individual study compared force-standardized (14 decanewton) and pressure-standardized (10 kilopascal) compressions in 433 participants.
- Patient pain was assessed using a numerical rating scale (NRS), and image quality was evaluated by radiologists.
Main Results:
- Pressure-standardized compression (≥5 daN) resulted in increased compressed breast thickness (4.2%-6.3%).
- Average pain scores decreased by 10%-17%, and severe pain (NRS≥7) was reduced by 27%-32% with pressure-standardized compression.
- Average glandular dose (AGD) and retake proportions were similar between the two protocols.
Conclusions:
- Pressure-standardized mammography compression significantly reduces patient pain without compromising image quality or radiation dose.
- This personalized approach offers a more comfortable and effective mammography screening experience.
- The validated contact area detector facilitates the implementation of pressure-standardized compression.
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