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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Cancer Prevention02:59

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Population-Level Outcomes for Screening Program Cancers in First Nations People in Ontario, Canada.

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Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project.

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Related Experiment Video

Updated: Jun 30, 2026

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Published on: August 18, 2016

Canadian Women's Attitudes Toward Receiving Personalized Breast Cancer Risk Information: Insights From the

Jennifer D Brooks1, Kristina M Blackmore2, Nguyet N M Ngo1

  • 1Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

Clinical Breast Cancer
|February 5, 2026
PubMed
Summary
This summary is machine-generated.

Most women positively received learning their breast cancer risk category and screening plan. Clear communication and provider support are key for successful risk-stratified screening implementation.

Keywords:
Breast cancer risk-stratified screeningBreast screeningPerceived riskPersonalized risk communicationRisk prediction

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Area of Science:

  • Oncology
  • Public Health
  • Genetics

Background:

  • Risk-stratified breast cancer screening offers an alternative to traditional age-based methods.
  • The Canadian PERSPECTIVE I&I project investigated women's perceptions of personalized risk information.

Purpose of the Study:

  • To assess women's attitudes towards learning their breast cancer risk category and associated screening plans.
  • To identify factors influencing these attitudes in a Canadian population.

Main Methods:

  • Multifactorial risk assessments using the CanRisk tool were conducted on 3319 women aged 40-69 in Ontario and Quebec.
  • Participants completed questionnaires on their attitudes toward risk communication at multiple time points.
  • Multinomial logistic regression analyzed participant characteristics associated with attitudes.

Main Results:

  • Most women (72.9%) perceived "Easing worry" as an advantage of knowing their risk.
  • Higher-risk participants were less likely to report reduced worry.
  • Visible minority status and lower education attainment were associated with perceiving risk information as "complicated."
  • Ontario participants were more likely than Quebec participants to consider the information "not wanted."

Conclusions:

  • The majority of women responded favorably to personalized breast cancer risk information and screening plans.
  • Effective implementation necessitates clear communication strategies, robust healthcare provider support, and regional resource alignment.