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Updated: Apr 19, 2026
Acrylic Resin Molding Based Head Fixation Technique in Rodents
Published on: January 12, 2016
Description of a Rat Palatal Acrylic Plate That Can Be Relined
Lissandra Matos Bról Meister1, Michele Bail1,2, Cláudia Viviane Guimarães Pellissari1
1Department of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil.
Purpose:
The objective of this article is to describe a method to construct an intraoral acrylic device that permits a reline material to be added to the inner surface of the palatal plate.
Materials And Methods:
Fifteen 60-day-old adult female rats (Rattus Norvegicus Albinus Wistar), weighing 150 to 250 g were used for this study and allocated to three groups (n = 5): G1, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) for 14 days; G2, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) relined with Tokuyama Rebase II for 14 days; and G3, animals maintained under the same conditions as the experimental groups, without wearing palatal plates for 14 days. The manipulation of the animals followed the guidelines of the Brazilian College of Animal Experimentation, under the approval of the animal ethics committee of the State University of Ponta Grossa. The palatal plates covered the whole palate, were fixed in the molar region with light-cured resin, and were kept there for 14 days. The animals received a paste diet and water ad libitum. Before and after the trial period, the rats were weighed individually on a precision scale. Statistical analysis was performed using a two-way analysis of variance (α = 0.05) test for comparison of the animals' weight (g) at time 0 and after 14 days of using the palatal plate.
Results:
No statistical differences were observed regarding the weight of the animals among the experimental groups in the study.
Conclusions:
The individual master impressions, the molar teeth coverage, and the method of cementation with nonadhesive composite resin provided good stability for the palatal plate showed in this study, not disturbing the eating habits and nutrition of the animals. This model seems reproducible, offering adequate histopathological evaluation. Differences in tissue morphology exist between the animals that used the palatal plate and the animals that did not use this device. Use of these palatal plates could clarify how prostheses bring changes in the palatal mucosa of users.
