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The impact of antibiotic-impregnated catheters on ventriculoperitoneal shunt infection

Mehmet Sorar1, Uygur Er, Pmar Özişik

  • 1Department of Neurology Clinic, Dışkapı Education and Research Hospital, Turkey.

Turkish Journal of Medical Sciences
|January 7, 2015
PubMed
Abstract

Insights

Antibiotic-impregnated shunts significantly reduced shunt infections in pediatric hydrocephalus patients. This study found zero infections with impregnated catheters versus 6% with standard ones over 26 months.

Area of Science:

  • Neurosurgery
  • Pediatric Infectious Diseases
  • Biomedical Engineering

Background:

  • Ventriculoperitoneal shunt infections are a significant complication, often caused by skin flora colonizing shunt components.
  • Antibiotic-impregnated shunts are a preventative measure against such colonization.
  • Hydrocephalus management in children necessitates effective strategies to minimize shunt-related complications.

Purpose of the Study:

  • To evaluate the incidence of shunt infection in pediatric patients receiving antibiotic-impregnated shunts.
  • To compare infection rates between antibiotic-impregnated and non-impregnated shunt catheters in children with hydrocephalus.

Main Methods:

  • Retrospective review of pediatric patients undergoing cerebrospinal fluid shunt insertion between May 2004 and December 2010.
  • Analysis of 211 shunt placement procedures in 123 patients, differentiating between impregnated and non-impregnated catheters.
  • Follow-up for an average of 26.2 months to assess shunt infection rates.

Main Results:

  • A total of 193 non-impregnated shunts and 18 antibiotic-impregnated shunts were placed.
  • Shunt infection occurred in 6% (12 patients) of those with non-impregnated catheters.
  • No shunt infections were observed in patients who received antibiotic-impregnated catheters (P < 0.01).

Conclusions:

  • Antibiotic-impregnated catheters significantly decrease the incidence of shunt infections in pediatric hydrocephalus patients postoperatively.
  • These catheters are effective in preventing perioperative colonization of shunt components.
  • The use of antibiotic-impregnated catheters represents a valuable advancement in reducing shunt-related morbidity.

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