Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

41.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
41.3K
Bone Disorders01:29

Bone Disorders

8.8K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.8K
The Bone Matrix01:18

The Bone Matrix

10.2K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
10.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

4.3K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
4.3K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

7.4K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
7.4K
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

10.7K
10.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of the Behavioral Change and Utility Features of Electronic Activity Monitors.

Technologies·2025
Same author

Assessing the Suitability of a Virtual 'Pink Warrior' for Older Breast Cancer Survivors during COVID-19: A Pilot Study.

Life (Basel, Switzerland)·2023
Same author

Feasibility and Acceptability of an Active Video Game-Based Physical Activity Support Group (Pink Warrior) for Survivors of Breast Cancer: Randomized Controlled Pilot Trial.

JMIR cancer·2022
Same author

Effect of Electronic Activity Monitors and Pedometers on Health: Results from the TAME Health Pilot Randomized Pragmatic Trial.

International journal of environmental research and public health·2020
Same author

The Effects of Loaded Plyometric Exercise during Warm-Up on Subsequent Sprint Performance in Collegiate Track Athletes: A Randomized Trial.

Sports (Basel, Switzerland)·2020
Same author

The utility of wearable fitness trackers and implications for increased engagement: An exploratory, mixed methods observational study.

Digital health·2020
Same journal

Proximal Calf Muscle Cross-Sectional Area After Anterior Cruciate Ligament Reconstruction: A Longitudinal MRI Evaluation.

Journal of sport rehabilitation·2026
Same journal

We Thought You'd Never Ask: Insights From the Health of Elite Retired Australian Female Athletes Survey.

Journal of sport rehabilitation·2026
Same journal

Physical Factors Associated With Chronic Low Back Pain in Collegiate Baseball Players: A Cross-Sectional Study.

Journal of sport rehabilitation·2026
Same journal

Validity and Reliability of a Modified Seated Athletic Shoulder Test Using a Functional Electromechanical Dynamometer.

Journal of sport rehabilitation·2026
Same journal

Reliability of Inertial Sensors for Measuring Scapular Kinematics in Individuals With Shoulder Pain and Scapular Dyskinesis.

Journal of sport rehabilitation·2026
Same journal

Comment on: "Sequential Changes in Scapular Range of Motion After an Intervention Using the KOJI AWARENESS Original 'Wall Angel Slider' Exercise".

Journal of sport rehabilitation·2026
See all related articles

Related Experiment Video

Updated: Apr 19, 2026

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.8K

Intermittent Pneumatic Compression and Bone Mineral Density: An Exploratory Study.

Hawley Chase Almstedt1, Zakkoyya H Lewis

  • 1Dept of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA.

Journal of Sport Rehabilitation
|January 7, 2015
PubMed
Summary
This summary is machine-generated.

Intermittent pneumatic compression (IPC) may improve bone mineral density (BMD) at the hip. This study found that IPC treatment led to a modest increase in BMD in the treated leg, while the untreated leg showed a decrease.

More Related Videos

Author Spotlight: Enhancing Small Animal Bone Compression Testing for Research
07:52

Author Spotlight: Enhancing Small Animal Bone Compression Testing for Research

Published on: December 1, 2023

2.5K
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.6K

Related Experiment Videos

Last Updated: Apr 19, 2026

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.8K
Author Spotlight: Enhancing Small Animal Bone Compression Testing for Research
07:52

Author Spotlight: Enhancing Small Animal Bone Compression Testing for Research

Published on: December 1, 2023

2.5K
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.6K

Area of Science:

  • Orthopedics
  • Physiology
  • Biomedical Engineering

Background:

  • Intermittent pneumatic compression (IPC) is widely used for swelling and thrombosis prevention.
  • Emerging evidence suggests IPC may aid fracture rehabilitation and bone remodeling.

Purpose of the Study:

  • To assess the feasibility of using IPC on bone mineral density (BMD) in noninjured volunteers.
  • To explore the novel application of IPC for bone health.

Main Methods:

  • A within-subjects design was employed in a university research laboratory setting.
  • Nine noninjured participants received IPC treatment (60 mm Hg) on one leg for 1 hour daily, 5 days/week, over 10 weeks.
  • Dual-energy X-ray absorptiometry measured hip BMD before and after the intervention; anthropometrics, physical activity, and nutrient intake were also monitored.

Main Results:

  • Participants completed an average of 43.4 sessions over 9.6 weeks.
  • Significant time-by-treatment effects were observed at the femoral neck (P=.023), trochanter (P=.027), and total hip (P=.008).
  • The treated hip showed an average BMD increase of 0.5-1.0%, while the untreated hip decreased by 0.7-1.9%.

Conclusions:

  • Intermittent pneumatic compression (IPC) appears safe and feasible for investigating its effects on bone health.
  • This exploratory study suggests a potential role for IPC in optimizing bone mineral density.