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Updated: Apr 19, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
Movement disorders in 2014. Genetic advances spark a revolution in dystonia phenotyping
Tom J de Koning1, Marina A J Tijssen1
1University of Groningen, University Medical Center Groningen, Departments of Genetics and Neurology, PO Box 30.001, 9700 RB Groningen, Netherlands.
Abstract:
Genetic revelations in 2014 are testing traditional classification systems for movement disorders, and our approach to clinical diagnostics. Mutations in dystonia-associated genes lead to a spectrum of disorders with different phenotypes, underscoring the need for stringent clinical phenotyping of patients with movement disorders, as well as next-generation sequencing approaches.
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