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Updated: Apr 18, 2026

08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
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Microdosimetry spectra and relative biological effectiveness of 15 and 30MeV proton beams
Abstract:
The relative biological effectiveness (RBE) of high-energy protons has been well investigated, but estimates of RBE for lower-energy (<40MeV) protons are scarce. In the present work, measurements were made of the lineal energy spectra using a home-made miniature tissue-equivalent proportional counter for 15 and 30MeV protons from the TR 30/15 cyclotron. Monte Carlo simulations were made for the same spectra using the FLUKA code. These spectra were coupled to several biological models to evaluate the RBE for various biological endpoints.
Keywords:
FLUKA codeLineal energyRelative biological effectivenessTR 30/15 cyclotronTissue equivalent proportional counter
