Related Experiment Video
Updated: Apr 18, 2026
08:26
Author Spotlight: Advancing Personalized Medicine in Ovarian Cancer
Published on: February 23, 2024
2.9K
Personalized medicine and cancer
1Epidemiology and Genetics Research Program (EGRP), Division of Cancer Control and Population Sciences, National Cancer Institute (NCI), National Institutes of Health (NIH), 6130 Executive Boulevard, Rockville, MD 20852, USA. vermam@mail.nih.gov.
Journal of Personalized Medicine
|January 7, 2015
Summary
Personalized medicine uses molecular profiling to tailor cancer care. Companion diagnostics guide treatment selection and dosage for individual patient needs, improving outcomes.
Area of Science:
- Oncology
- Genomics
- Pharmacogenomics
Background:
- Cancer remains a leading cause of death in the US, with millions affected annually.
- Advances in genomics and molecular profiling have spurred the growth of personalized medicine.
- Understanding individual patient profiles is key to optimizing healthcare.
Purpose of the Study:
- To discuss recent advances in personalized medicine for cancer.
- To explore challenges and future perspectives in this field.
- To highlight the role of molecular profiling and companion diagnostics.
Main Methods:
- Systematic use of genetic and molecular information for patient care.
- Molecular profiling of healthy and cancer patient samples.
- Development and application of companion diagnostics for targeted therapies.
Main Results:
- Personalized medicine allows for tailored preventative and therapeutic strategies.
- Companion diagnostics stratify disease, select medications, and optimize dosages.
- Molecular profiling enhances the potential for individualized medical care.
Conclusions:
- Personalized medicine, driven by molecular profiling and companion diagnostics, offers a powerful approach to cancer treatment and prevention.
- Tailoring medical care to individual needs is crucial for improving patient outcomes.
- Continued research and development are essential for advancing personalized oncology.
More Related Videos
Related Concept Videos
02:50Combination Therapies and Personalized Medicine
6.4K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
6.4K
02:50Combination Therapies and Personalized Medicine
1.9K
1.9K
02:57Targeted Cancer Therapies
1.8K
1.8K
02:57Targeted Cancer Therapies
9.2K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
9.2K
02:18Cancer
56.4K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
56.4K
02:49Cancer Therapies
10.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.9K