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Updated: Apr 18, 2026

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
[Idiopathic intracranial hypertension and obesity]
M Tirza Naarden1, Alie Schuitemaker, Hilde M H Braakman
1St. Antonius Ziekenhuis, afd. Neurologie, Nieuwegein.
Insights
Medication-induced weight gain can trigger idiopathic intracranial hypertension (IIH), a condition causing vision loss. Prompt treatment, including weight management and medication review, is crucial for recovery and preventing permanent vision impairment.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure without identifiable brain abnormalities.
- IIH predominantly affects overweight young women, presenting with symptoms like headache, nausea, vomiting, and visual disturbances.
Background:
Idiopathic intracranial hypertension (IIH) is a neurological syndrome characterized by elevated intracranial pressure in the absence of intracerebral abnormalities or hydrocephalus.
Case Description:
A 17-year-old girl gained more than 25 kg in weight during treatment with risperidone and subsequently developed headache, diplopia and loss of vision due to IIH. After insertion of a ventriculoperitoneal drain and discontinuation of risperidone she lost weight and her symptoms improved. Her visual functions recovered almost fully during follow-up.
Conclusion:
Patients with IIH are mainly overweight young women who present with raised intracranial pressure evidenced by headache, nausea, vomiting and vision disturbances. Prescribed medication-induced weight gain may lead to IIH. Treatment of IIH should be focused on the prevention of severe and irreversible loss of vision.
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