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Updated: Apr 18, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

Segmental neurofibromatosis.

Virat Galhotra¹, Soheyl Sheikh², Sanjeev Jindal³

¹Department of Pedodontics and Preventive Dentistry, Gian Sagar Dental College and Hospital, Vill, Ramnagar, Banur, Punjab, India.

Indian Journal of Dentistry

|January 8, 2015

Summary

Segmental neurofibromatosis, a rare condition causing skin lesions in one body area, is exceptionally uncommon on the face. This case highlights facial segmental neurofibromatosis involving the mouth, cheek, ear, and neck.

Keywords:

Segmental neurofibromatosis neurofibromas von Recklinghausen syndrome

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Area of Science:

Dermatology
Genetics
Oncology

Background:

Segmental neurofibromatosis is a rare genetic disorder.
It is characterized by localized neurofibromas or café-au-lait macules.
It affects only one region of the body.

Observation:

Facial occurrence of segmental neurofibromatosis is extremely rare.
Few cases have been documented previously.
This report details a unique case involving the right side of the face.

Findings:

The patient presented with neurofibromas and café-au-lait macules.
Lesions were confined to the buccal mucosa, tongue, cheek, ear, and neck.
The presentation was unilateral, affecting the right side of the face.

Implications:

This case expands the understanding of segmental neurofibromatosis presentation.
It underscores the importance of considering rare conditions in facial diagnoses.
Further research may elucidate the specific genetic or developmental factors involved in facial neurofibromatosis.