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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Published on: July 11, 2013

Phototherapy for atopic dermatitis.

Sunil Dogra¹, Rahul Mahajan,

¹Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Indian Journal of Dermatology, Venereology and Leprology

|January 9, 2015

Summary

This summary is machine-generated.

Phototherapy and photochemotherapy, including UVA1 and narrow-band UVB (NB-UVB), effectively treat atopic dermatitis. NB-UVB is recommended for chronic eczema, while UVA1 may be better for acute flares.

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Area of Science:

Dermatology
Photomedicine

Background:

Atopic dermatitis (eczema) is a chronic inflammatory skin condition.
Phototherapy and photochemotherapy are established treatment modalities for atopic dermatitis.

Purpose of the Study:

To review the literature on the effectiveness of phototherapy and photochemotherapy for atopic dermatitis.
To provide evidence-based recommendations for the clinical use of these treatments.

Main Methods:

A comprehensive literature search was conducted in PubMed, EMBASE, and the Cochrane Library up to March 2014.
Included studies were systematic reviews, meta-analyses, guidelines, RCTs, and observational studies on phototherapy for atopic dermatitis.

Main Results:

38 studies out of 688 evaluated met the inclusion criteria.
Both UVA1 and narrow-band UVB (NB-UVB) significantly reduce eczema severity.
Medium-dose UVA1 shows comparable efficacy to high-dose and superior efficacy to low-dose UVA1.

Conclusions:

UVA1 is preferred for acute flares, while NB-UVB is recommended for chronic eczema, particularly in adults.
NB-UVB is superior to broad-band UVB (BB-UVB).
In children, NB-UVB is a second-line therapy due to potential long-term side effects.