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Updated: Apr 18, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
Linkage disequilibrium estimates of contemporary N e using highly variable genetic markers: a largely untapped
1NOAA Fisheries, Northwest Fisheries Science Center Seattle, WA, USA.
Abstract:
Genetic methods are routinely used to estimate contemporary effective population size (N e) in natural populations, but the vast majority of applications have used only the temporal (two-sample) method. We use simulated data to evaluate how highly polymorphic molecular markers affect precision and bias in the single-sample method based on linkage disequilibrium (LD). Results of this study are as follows: (1) Low-frequency alleles upwardly bias [Formula: see text], but a simple rule can reduce bias to
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