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Related Experiment Video

Updated: Apr 18, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Pelvic neurofibroma.

Girish D Bakhshi¹, Mukund B Tayade¹, Rajesh B Yadav¹

¹Department of General Surgery, Grant Medical College and Sir J. J. Group of Hospitals , Byculla, Mumbai, India.

Clinics and Practice

|January 9, 2015

Summary

This summary is machine-generated.

A neurofibroma, a type of tumor, was found in the pelvic retroperitoneum of a 58-year-old male. This case suggests these pelvic tumors can develop independently of any organ involvement.

Keywords:

neurofibroma pelvis retroperitoneum

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Area of Science:

Oncology
Surgical Pathology

Background:

Retroperitoneal masses can present as challenging diagnostic dilemmas.
Neurofibromas are benign nerve sheath tumors, typically associated with neurofibromatosis.

Observation:

A 58-year-old male presented with a palpable lower abdominal mass extending into the pelvis.
Imaging (CT scan) identified a large pelvic retroperitoneal mass.
Exploratory laparotomy revealed a well-encapsulated mass posterior to the bladder, displacing adjacent structures.

Findings:

Histopathological examination confirmed the mass as a neurofibroma.
No evidence of organ involvement was found on imaging or during surgery.
This suggests a de novo origin for the pelvic neurofibroma.

Implications:

This case highlights the possibility of de novo pelvic neurofibromas, independent of specific organ origins.
Understanding the varied origins of retroperitoneal tumors is crucial for accurate diagnosis and surgical planning.
Further research into the etiology of de novo retroperitoneal neurofibromas may be warranted.