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A Rare Case of Primary Mesenteric Liposarcoma.
Priya Ahire1, Aldrin L Myrthong1, Suresh Mahankudo2
1General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, IND.
Cureus
|June 1, 2023
Summary
A rare mesenteric liposarcoma case highlights successful treatment. Surgery combined with chemotherapy (doxorubicin, ifosfamide, mesna) led to a good outcome with no recurrence.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Primary mesenteric liposarcoma is a rare malignant soft tissue neoplasm.
- Desmoid tumors can present as abdominal masses, requiring careful histopathological diagnosis.
Observation:
- A 42-year-old male presented with abdominal pain and a mesenteric mass initially suspected as a desmoid tumor.
- Histopathology confirmed dedifferentiated liposarcoma, with immunohistochemistry positive for MDM2, p16, and CD34.
Findings:
- Surgical excision of the large mesenteric tumor was performed.
- Adjuvant chemotherapy with doxorubicin, ifosfamide, and mesna was administered post-operatively.
Implications:
- This case demonstrates the effectiveness of a combined surgical and chemotherapeutic approach for mesenteric liposarcoma.
- Early diagnosis and multimodal treatment are crucial for favorable clinical outcomes in rare soft tissue neoplasms.

