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A CuS-based chemical tongue chip for pattern recognition of proteins and antibiotic-resistant bacteria

Xiang Ran1, Fang Pu, Jinsong Ren

  • 1Laboratory of Chemical Biology, State Key laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Changchun, Jilin 130022, China. pufang@ciac.ac.cn jren@ciac.ac.cn.

Chemical Communications (Cambridge, England)
|January 10, 2015
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Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and...
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