Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

Gene Evolution - Fast or Slow?

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...

Gene Evolution - Fast or Slow?

Gene Evolution - Fast or Slow?

Applications of Molecular Taxonomy

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

Phylogeny

Phylogeny

Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.

Phylogenetic Trees

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Min-frame transformation enables more sensitive viral genome alignment.

bioRxiv : the preprint server for biology·2026

Same author

TIPP-SD: A new method for species detection in microbiomes.

PLoS computational biology·2026

Same author

Phylogenetic Placement Using SCAMPP and Batch-SCAMPP.

Methods in molecular biology (Clifton, N.J.)·2026

Same author

The Earth BioGenome Project Phase II: illuminating the eukaryotic tree of life.

Frontiers in science·2026

Same author

BiRNA-BERT allows efficient RNA language modeling with adaptive tokenization.

Communications biology·2025

Same author

BioLLMNet: enhancing RNA-interaction prediction with a specialized cross-LLM transformation network.

Briefings in bioinformatics·2025

Same journal

Chromosomal scale genome assembly of medicinal plant Sophora tonkinensis.

BMC genomics·2026

Same journal

Variant-specific RNA testing resolves variants of uncertain significance in exome testing.

BMC genomics·2026

Same journal

Kaiso overexpression promotes an interferon immune response in murine intestines.

BMC genomics·2026

Same journal

Genomic evidence of ecological flexibility and cross-niche CRISPR spacerome targeting phage-plasmid hybrids in Latilactobacillus curvatus.

BMC genomics·2026

Same journal

Fgf evolution in vertebrates: insights from cyclostomes.

BMC genomics·2026

Same journal

Metabolic reprogramming, oxidative stress, and mitophagy in JSRV Env-transformed BEAS-2B cells: insights from integrated transcriptomics and metabolomics.

BMC genomics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Disk covering methods improve phylogenomic analyses.

Md Shamsuzzoha Bayzid, Tyler Hunt, Tandy Warnow

|January 10, 2015

Summary

This summary is machine-generated.

We developed a new method to speed up species tree inference, a key task in evolutionary biology. This approach enhances the accuracy of phylogenetic trees, even with large genomic datasets.

More Related Videos

Optimization and Comparative Analysis of Plant Organellar DNA Enrichment Methods Suitable for Next-generation Sequencing

Optimization and Comparative Analysis of Plant Organellar DNA Enrichment Methods Suitable for Next-generation Sequencing

Published on: July 28, 2017

A Practical Guide to Phylogenetics for Nonexperts

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Related Experiment Videos

Last Updated: Apr 18, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Optimization and Comparative Analysis of Plant Organellar DNA Enrichment Methods Suitable for Next-generation Sequencing

Optimization and Comparative Analysis of Plant Organellar DNA Enrichment Methods Suitable for Next-generation Sequencing

Published on: July 28, 2017

A Practical Guide to Phylogenetics for Nonexperts

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Area of Science:

Bioinformatics
Evolutionary Biology
Phylogenetics

Background:

Species tree inference from genomic data is crucial for understanding evolution.
Gene tree discordance, often caused by incomplete lineage sorting (ILS), complicates accurate species tree estimation.
Existing coalescent-based methods like MP-EST face scalability challenges with increasing species numbers.

Purpose of the Study:

To improve the scalability and accuracy of the MP-EST species tree estimation method.
To enable efficient phylogenetic analysis on large genomic datasets.

Main Methods:

Implemented divide-and-conquer techniques to optimize MP-EST.
Applied the enhanced method to simulated and biological datasets.

Main Results:

The divide-and-conquer approach significantly improves MP-EST's scalability for large datasets.
The enhanced MP-EST method demonstrates improved accuracy in species tree estimation.
Performance gains were validated on both simulated and real biological data.

Conclusions:

Divide-and-conquer strategies offer an effective solution for scaling coalescent-based phylogenetic methods.
The enhanced MP-EST method provides a more accurate and efficient tool for species tree inference.
This work facilitates robust evolutionary analyses in the era of big genomic data.