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Updated: Apr 18, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Endpoints and cutpoints in head and neck oncology trials: methodical background, challenges, current practice and

Marcus Hezel1, Kathrin von Usslar2, Thiemo Kurzweg3

  • 1Department of Otorhinolaryngology, Head and Neck Surgery and Oncology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. m.hezel@uke.de.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|January 10, 2015
PubMed
Summary

This review covers the methodical and statistical foundations for clinical trial design, emphasizing endpoint selection for evidence-based medicine and head and neck cancer research.

Keywords:
Clinical studyClinical trialCutpointEndpointGood practiceHead and neck cancer

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