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Updated: Apr 18, 2026
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Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
Published on: October 3, 2025
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Curettage and Asherman's syndrome-lessons to (re-) learn?
Ashley R Gilman Barber1, Stephanie A Rhone2, Margo R Fluker2
1Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver BC.
Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC
|January 10, 2015
Summary
Asherman's syndrome occurred in 0.7% of women undergoing early pregnancy failure management. Sharp curettage, especially repeat procedures, increases Asherman's syndrome risk.
Area of Science:
- Reproductive Medicine
- Gynecologic Surgery
- Obstetrics
Background:
- Asherman's syndrome, characterized by intrauterine adhesions, can impair fertility.
- A cluster of Asherman's syndrome cases prompted an investigation at a tertiary care institution.
Purpose of the Study:
- To investigate a cluster of Asherman's syndrome cases.
- To identify risk factors associated with Asherman's syndrome in early pregnancy management.
Main Methods:
- A practice audit was conducted, including chart review of index cases.
- Treatment choices for new patient referrals over 18 months were compiled.
- Diagnosis combined clinical symptoms and hysteroscopic findings of intrauterine adhesions.
Main Results:
- Six out of 844 (0.7%) women undergoing active management for early pregnancy failure developed Asherman's syndrome.
- All six women had undergone sharp curettage, with three requiring repeat procedures.
- No Asherman's syndrome cases were reported after manual vacuum aspiration or medical management with misoprostol.
Conclusions:
- Asherman's syndrome is a risk following dilatation and curettage for spontaneous abortion management.
- Sharp and repeated curettage are significant risk factors and should be used cautiously.
- Identifying common risk factors can guide practice changes to mitigate Asherman's syndrome incidence.
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