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Related Experiment Videos

Bayram Kelle1, Fatih Yıldız2, Semra Paydas3

  • 1Departamento de Medicina Física e Reabilitação da Faculdade de Medicina da Universidade Cukurova, Adana, Turquia.

Revista Brasileira De Reumatologia
|January 12, 2015
PubMed
Summary

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Hypertrophic osteoarthropathy (HOA) is a rare condition causing joint pain and bone changes. This report details a case of HOA coexisting with myelofibrosis, offering insights into this rare association.

Area of Science:

  • Rheumatology
  • Hematology
  • Oncology

Background:

  • Hypertrophic osteoarthropathy (HOA) presents with joint pain, digital clubbing, and periosteal reactions.
  • Primary HOA is hereditary and appears early in life.
  • Secondary HOA is associated with inflammatory and malignant conditions, often resolving with treatment of the underlying disease.

Purpose of the Study:

  • To report a rare case of hypertrophic osteoarthropathy (HOA) coexisting with myelofibrosis.
  • To review the current literature on HOA associated with myeloproliferative neoplasms.

Main Methods:

  • Case presentation of a patient with coexisting HOA and myelofibrosis.
  • Comprehensive literature review on secondary HOA and its association with myelofibrosis.
Keywords:
Baqueteamento digitalClubbingHypertrophic osteoarthropathyInterferonMielofibroseMyelofibrosisOsteoartropatia hipertróficaPeriostitePeriostitis

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Main Results:

  • The case highlights the coexistence of HOA and myelofibrosis, a rare clinical presentation.
  • Literature review confirms that secondary HOA can be associated with various hematological malignancies, including myelofibrosis.

Conclusions:

  • HOA can be a manifestation of underlying myelofibrosis.
  • Recognition of HOA in patients with myelofibrosis is crucial for comprehensive patient management and may offer prognostic insights.