Related Experiment Video
Updated: Apr 18, 2026

13:42
Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
Published on: January 19, 2014
14.4K
Scabies
1Department of Dermatology, Geisinger Health System, State College, Pennsylvania, USA. llrosamilia@geisinger.edu
Seminars in Cutaneous Medicine and Surgery
|January 13, 2015
Summary
Scabies is a complex skin infestation influenced by the mite, host, and environment. This review updates on scabies variations, diagnosis, and treatment options for effective management.
Area of Science:
- Dermatology
- Parasitology
- Public Health
Background:
- Scabies is a neglected tropical disease caused by the mite Sarcoptes scabiei.
- Diagnosis and treatment are challenging due to varied clinical presentations and drug resistance.
- Effective scabies control requires understanding the mite-host-environment interaction.
Purpose of the Study:
- To provide an updated review of scabies.
- To discuss clinical variations, diagnostic methods, and management strategies.
- To highlight challenges in scabies eradication.
Main Methods:
- Literature review of recent studies on scabies.
- Analysis of diagnostic techniques, including microscopy and molecular methods.
- Evaluation of current and emerging treatment options.
Main Results:
- Scabies presents with diverse clinical manifestations, complicating diagnosis.
- Diagnostic accuracy remains a challenge, necessitating improved methods.
- Drug resistance and resource limitations impact treatment efficacy.
Conclusions:
- Integrated approaches are needed for scabies control.
- Further research into novel diagnostics and therapeutics is crucial.
- Public health strategies must address environmental and host factors.
Related Concept Videos
Skin Diseases and Disorders
6.3K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.3K
Acne Infection
75
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
75
Accessory Structures of the Skin: Sebaceous Glands
5.9K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.9K
Accessory Structures of the Skin: Hair and Hair Follicles
5.9K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
5.9K
Staphylococcal Skin Infections
110
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
110
The Skin Microbiota
93
The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
93

