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Updated: Apr 18, 2026

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Published on: January 31, 2025
Comparing epidural analgesia and ON-Q infiltrating catheters for pain management after hepatic resection
Jose M Soliz1, Rodolfo Gebhardt2, Lei Feng3
1M.D. Anderson Cancer Center, Department of anesthesiology and Perioperative Medicine, 1515 Holcombe Blvd. Unit 409, Houston, TX 77030, , , jsoliz@mdanderson.org.
Background And Objectives:
Pain control after hepatic resection presents unique challenges as subcostal incisions, rib retraction, and diaphragmatic irritation can lead to significant pain. Both epidural analgesia and ON-Q catheters have been used for postoperative pain management after hepatic surgery, but to our knowledge have not been directly compared.
Methods:
The records of 143 patient between the ages 18 and 70 were reviewed who underwent hepatic resection by a single surgeon. Patients were categorized according to method of postoperative pain control. Average pain scores for both study groups were collected until POD#3.
Results:
Demographic data and the length of surgery were similar between the groups (all p>0.05). On the day of surgery and POD#1, average pain scores for the epidural group were lower than the ON-Q group (P<0.0001 and P=0.0008 respectively). There was no difference in pain scores on POD #2 (P=.2369) or POD #3 (P=0.2289).
Conclusions:
Epidural analgesia provides superior pain control on the day of surgery and POD#1 when compared to On-Q catheter with IV PCA. There was no difference in pain scores on POD#2 or POD#3. Future prospective randomized trials comparing these analgesic methods will be required to further evaluate enhanced recovery after hepatic surgery.
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