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Structure and function of SET and MYND domain-containing proteins

Nicholas Spellmon1, Joshua Holcomb2, Laura Trescott3

  • 1Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, 540 East Canfield Street, Detroit, MI 48201, USA. nicholas.spellmon@wayne.edu.

International Journal of Molecular Sciences
|January 13, 2015
PubMed
Summary

Suppressor of variegation, Enhancer of Zeste, Trithorax (SET) and MYND (Myeloid-Nervy-DEAF1) domain-containing proteins (SMYD) are crucial epigenetic regulators involved in cell functions. This review explores their biological roles and structural data, highlighting therapeutic potential.

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