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Nocturnal enuresis: non-pharmacological treatments
1University of Alberta, Alberta, Canada.
Insights
Non-pharmacological interventions like enuresis alarms and dry bed training show promise for treating nocturnal enuresis (bedwetting). This systematic review evaluates their effectiveness and safety in children.
Area of Science:
- Pediatrics
- Urology
- Evidence-Based Medicine
Background:
- Nocturnal enuresis (bedwetting) is common, affecting up to 20% of 5-year-olds.
- Spontaneous resolution occurs in 15% of affected children annually.
- Treatment is generally not recommended for children under 7 years old.
Purpose of the Study:
- To systematically review the effectiveness and safety of non-pharmacological interventions for nocturnal enuresis.
Main Methods:
- A systematic review was conducted, searching major databases up to October 2013.
- Included studies evaluated interventions such as acupuncture, dry bed training, enuresis alarms, and hypnotherapy.
- GRADE evaluation assessed the quality of evidence for each intervention.
Main Results:
- Five studies met the inclusion criteria for the review.
- The review analyzed the effectiveness and safety of various non-pharmacological treatments.
Conclusions:
- Acupuncture, dry bed training, enuresis alarms, and hypnotherapy were identified as interventions for nocturnal enuresis.
- Information on the effectiveness and safety of these methods is presented.
Introduction:
Nocturnal enuresis affects 15% to 20% of 5-year-old children, 5% of 10-year-old children, and 1% to 2% of people aged 15 years and older. Without treatment, 15% of affected children will become dry each year. Nocturnal enuresis is not diagnosed in children younger than 5 years, and treatment may be inappropriate for children younger than 7 years.
Methods And Outcomes:
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of non-pharmacological interventions for relief of symptoms of nocturnal enuresis? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2013 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results:
We found five studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions:
In this systematic review, we present information relating to the effectiveness and safety of the following interventions: acupuncture, dry bed training, enuresis alarm, and hypnotherapy.
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