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Updated: Apr 18, 2026

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
NMR signal enhancement for hyperpolarized fluids continuously generated in hydrogenation reactions with parahydrogen
Danila A Barskiy1, Oleg G Salnikov, Kirill V Kovtunov
1International Tomography Center, Siberian Branch of the Russian Academy of Sciences, 3A Institutskaya Street, Novosibirsk, Russia , 630090.
Abstract:
In the present study we analyze the factors which can lower hyperpolarization of fluids produced in a continuous flow regime by the parahydrogen-induced polarization technique. We use the findings of this analysis to examine the flow rate dependence of propane hyperpolarization produced in the heterogeneous propylene hydrogenation by parahydrogen over Rh/TiO2 catalyst. We have estimated the maximum attainable propane (1)H hyperpolarization yield and the corrected percentage of pairwise hydrogen addition in heterogeneous hydrogenation, which was found to be ∼7%. The approach developed for polarization analysis is useful for the optimization of experimental setup and reaction conditions to obtain maximum hyperpolarization for parahydrogen-based catalyst-free continuously generated fluids applicable in biomedical magnetic resonance imaging.
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