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Hormonal regulation of collagen gene expression in osteoblastic cell-overview and new findings
B Kream1, J Harrison, R Bailey
1Department of Medicine, University of Connecticut Health Center, Farmington.
Connective Tissue Research
|January 1, 1989
Abstract:
Type I collagen synthesis in osteoblasts is regulated by a variety of systemic hormones, growth factors and locally produced factors. With the use of cDNA probes and hybridization analysis, it appears that many of these agents alter collagen synthesis by a pretranslational mechanism.