[Changes in the transsinusoidal fluid transfer in the cat liver during noradrenaline infusion]

The blood microcirculation and the lymph flow were studied in the cat hemodynamically isolated liver perfused under conditions of a regulated venous outflow and i.a. and intraportal administration of noradrenaline. An increase in the fluid transsinusoidal transfer revealed by the lymph flow acceleration in the liver, was determined by an increased hydrostatic pressure in the sinusoids at practically unaltered level of sinusoidal filtration. The above shifts were observed against the background of constriction of arterial, portal, venous and lymphatic vessels and of a decrease in capacitance of the liver vessels which were due to alpha-adrenocereptors excitation by noradrenaline.