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Tetrahydropyran- and tetrahydrofuran-containing diarylheptanoids from Hedychium coronarium rhizomes
Yi-Shan Lin1, Jung-Hsin Lin, Chia-Chuan Chang
1School of Pharmacy, College of Medicine, National Taiwan University , 33 Linsen South Road, Taipei 100, Taiwan, Republic of China.
Abstract:
Seven new diarylheptanoids (1-7) were isolated from the n-BuOH-soluble fraction of the rhizome of Hedychium coronarium. Hedycoropyrans A-C (1-3) contain a tetrahydropyran moiety, while hedycorofurans A-D (4-7) contain a tetrahydrofuran moiety, belonging to a rare structural class of diarylheptanoids. Their structures including stereochemistry were elucidated on the basis of 1D and 2D NMR and ECD spectroscopic analyses and HRESIMS data of the parent compounds and the isopropylidene derivatives of 4 and 7.
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