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Clinical features in liver cirrhosis patients who have experienced ischemic stroke

Kwang Min Kim1, Jong Woon Hwang, Sang Goon Shim

  • 1Division of Gastroenterology, Department of Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea. Sg0218.shim@samsung.com.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
|January 21, 2015
PubMed

Insights

Ischemic stroke occurs more frequently in patients with alcohol-induced liver cirrhosis, particularly those with less severe liver dysfunction. Most affected individuals had identifiable stroke risk factors like obesity or arrhythmia.

Area of Science:

  • Neurology
  • Hepatology
  • Cardiology

Background:

  • The incidence of ischemic stroke in liver cirrhosis patients is not well-established.
  • Liver cirrhosis is associated with various systemic complications.

Purpose of the Study:

  • To investigate the clinical characteristics of ischemic stroke in patients diagnosed with liver cirrhosis.
  • To identify potential risk factors and patterns of ischemic stroke in this population.

Main Methods:

  • Retrospective analysis of 23 patients with both ischemic stroke and liver cirrhosis.
  • Data collected over a 10-year period (January 2001 - December 2010).

Main Results:

  • Alcohol was the primary cause of liver cirrhosis in 60.8% of cases.
  • Child-Pugh Class B (39%) was most prevalent, followed by Class C (26%).
  • Common ischemic stroke risk factors included obesity (39.1%), arrhythmia (30.4%), and smoking history (30.4%).

Conclusions:

  • A notable frequency of ischemic stroke is observed in patients with alcohol-induced liver cirrhosis.
  • Patients with less compromised liver function (e.g., Child-Pugh Class B) showed a higher occurrence.
  • The majority of patients with ischemic stroke and liver cirrhosis had at least one identifiable risk factor.
Abstract

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