Facile syntheses of functionalized toll-like receptor 7 agonists
Babatope Akinbobuyi1, Matthew R Byrd1, Charles A Chang2
1Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798, USA.
Tetrahedron Letters
|January 21, 2015
Abstract:
Protein conjugates of toll-like receptor 7 agonists have been shown to elicit powerful immune responses. In order to facilitate our studies in this area our group has developed efficient syntheses for a number of functionalized derivatives that retain immune stimulatory activity.
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