Related Experiment Video

Updated: Apr 18, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.8K

[Varicella-zoster virus infection in a child complicated with bacterial pneumonia]

Benjamin Ole Wolthers1, Ebbe Thiested, Anette F Gyhrs

  • 1Børneafdelingen, Holbæk Sygehus, Smedelundsgade 40, 4400 Holbæk. benjaminowolthers@gmail.com.

Ugeskrift for Laeger
|January 24, 2015
PubMed

Insights

A pediatric case report highlights a severe bacterial pneumonia complication in a three-year-old girl with varicella-zoster virus. Prompt intervention with a lung drain led to recovery, questioning the role of varicella-zoster virus vaccination.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pulmonology

Background:

  • Varicella-zoster virus (VZV) infections can lead to serious complications.
  • Bacterial pneumonia is a recognized, though less common, sequela of VZV infection.
  • Atelectasis can result from severe pneumonia, impairing lung function.

Observation:

  • A three-year-old girl presented with VZV infection and severe bacterial pneumonia.
  • The patient initially did not respond to intravenous antibiotic therapy.
  • Atelectasis was present, indicating significant lung compromise.

Findings:

  • Insertion of a lung drain was crucial for the patient's recovery.
  • This case underscores the potential severity of bacterial pneumonia secondary to VZV.
  • The patient's response to drainage suggests a significant obstructive or exudative component to the pneumonia.

Implications:

  • Highlights the importance of considering bacterial pneumonia in VZV cases, especially with respiratory distress.
  • Suggests that prompt drainage may be necessary for managing severe VZV-associated pneumonia with atelectasis.
  • Raises awareness and prompts discussion regarding the potential benefits of VZV vaccination in preventing such severe complications.

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

3.4K
Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation08:04

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

Published on: July 9, 2014

16.4K

Related Concept Videos

Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
2
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.4K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.3K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
4.5K
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
4.1K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
1.1K