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Separation of the sodium and potassium currents from an action potential of a single active fiber
1Central Laboratory of Biophysics, Bulgarian Academy of Sciences, Sofia.
Abstract:
A method for calculation of the sodium and potassium currents of an active fiber is presented. The method includes the determination of the transmembrane ionic current, the sodium Nernst potential and the sodium conductivity as well. The method was illustrated by using an action potential of a single striated frog muscle fiber. The derivatives of the experimentally recorded action potential, necessary for calculation of the ionic current, were obtained by means of Fourier transform.