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[Value of the CRF test in primary and secondary adrenal insufficiency]
A Tabarin1, B Corcuff, M Dauthribes
1Service d'Endocrinologie, Hôpital Saint-André, Bordeaux.
Annales D'Endocrinologie
|January 1, 1989
Abstract:
The ACTH and cortisol responses after CRF administration were studied in 21 patients with adrenal failure and compared with those obtained in 15 control subjects. In patients with Addison's disease, cortisol and ACTH responses were respectively abolished or excessive. In patients with secondary adrenal failure, a unique bolus injection of CRF allows the differentiation between pituitary or hypothalamic secretory defect. With regard to previous reports, the usefulness of CRF test in primary and secondary adrenal failure is stressed.