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Updated: Apr 18, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Deep colonic endoscopic submucosal dissection using a modified clip and snare method incorporating a pre-looping
Ryosuke Ota1, Hisashi Doyama1, Kunihiro Tsuji1
1Department of Gastroenterology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan.
Endoscopic submucosal dissection (ESD) for colorectal cancer is challenging. A modified clip and snare technique with pre-looping was successfully applied in the deep colon, proving safe and efficient for large lesions.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic submucosal dissection (ESD) for colorectal cancer presents technical challenges compared to gastric cancer.
- Traction-assisted visualization of the submucosal layer is crucial for improving ESD outcomes.
Observation:
- A 57-year-old male presented with a 25mm laterally spreading cecal lesion (LST-GM).
- A modified clip and snare method, originally developed for gastric ESD, was adapted with a pre-looping technique for deep colonic application.
Findings:
- The modified deep colonic ESD procedure was completed successfully in 40 minutes.
- The technique resulted in no intra- or post-procedural complications.
Implications:
- This modified clip and snare technique with pre-looping facilitates deep colonic ESD.
- The approach shows promise for broader application in treating colorectal tumors via endoscopy.
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