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An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host-guest
Shunbi Xie1, Jin Zhang, Yali Yuan
1Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education (Southwest University), College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yuanruo@swu.edu.cn.
Chemical Communications (Cambridge, England)
|January 27, 2015
Abstract:
Here we have developed a "signal-on" peptide cleavage-based assay to directly transduce the peptide cleavage events into electrochemical signals via the host-guest interaction between ferrocene (Fc) and β-cyclodextrin (β-CD) for prostate specific antigen (PSA) detection.
