Recoupling of right and left ventricle pump function after surgical ventricle restoration: a cardiac magnetic
Francesco Secchi1, Marcello Petrini, Giovanni Di Leo
1Unità di Radiologia, IRCCS Policlinico San Donato, Piazza E. Malan, 20097, San Donato Milanese, Milano, Italy, francesco.secchi@grupposandonato.it.
Abstract:
To evaluate biventricular pump function after surgical ventricle restoration (SVR) using cardiac magnetic resonance (CMR). We retrospectively studied 39 patients who performed 1.5-T CMR before/after SVR acquiring short-axis ECG-gated cine sequences. End-diastolic, end-systolic, and stroke volume indexed to body surface area (EDVI, ESVI, and SVI), ejection fraction (EF), and their modification after SVR (∆) were obtained for right ventricle (RV) and left ventricle (LV). Wilcoxon signed rank test and Spearman correlation coefficient were used; EF reproducibility was estimated. Median LVEF increased from 24% [interquartile range (IQR) 19-31%] before SVR to 34% (IQR 29-43%) after SVR (P < 0.001). Median RVEF remained unchanged from 58% (IQR 48-66%) before SVR to 57% (IR 46-64%) after SVR (P = 0.743). The correlation between LVEF and RVEF was not significant before SVR (r = 0.182; P = 0.266) but significant after SVR (r = 0.445; P = 0.005). The ∆RVEF was positively correlated with ∆LVEF (r = 0.558; P < 0.001). ∆RVSVI was positively correlated with ∆LVSVI (r = 0.502; P = 0.001). LVEF reproducibility before SVR was 97% for both intra- and inter-reader reproducibility; RVEF reproducibility was 96 and 93%, respectively. SVR improved LV function without apparent impact on RV function. After SVR the two ventricles showed a functional recoupling. Reproducibility of CMR EF was excellent for both ventricles.
