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Updated: Apr 18, 2026
A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Oral amelanotic melanoma of the maxilla
Nasrollah Saghravanian1, Mahdi Pazouki2, Maryam Zamanzadeh3
1Associated Professor, Department of Oromaxillofacial Pathologist, Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mash-had University of Medical Sciences, Mashhad, Iran.
Abstract:
Amelanotic melanoma is a variant of malignant melanoma comprising 2% to 8% of all malignant melanomas. The amelanotic presentation of melanoma in the oral cavity is extremely rare and has been reported only occasionally in the literature. Moreover, the lack of melanin makes these tumors difficult to diagnose than that of pigmented lesions and the prognosis tends to be poorer. Herein, we report an amelanotic melanoma involving the oral mucosa of the maxilla in a 27 year-old male.
