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The human cytochrome P450 CYP3 locus: assignment to chromosome 7q22-qter
N K Spurr1, A C Gough, K Stevenson
1Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, Herts, UK.
Human Genetics
|January 1, 1989
Abstract:
The cytochrome P-450s are a large multigene family of enzymes involved in the metabolism and detoxification of drugs and chemicals. Using a full length cDNA clone for the human nifedipine oxidase gene (CYP3) and a panel of human-rodent somatic cell hybrids, we have assigned this gene family to chromosome 7q22-qter. A search for RFLPs using this probe yielded no results.