Related Experiment Video
Updated: Apr 18, 2026
06:20
Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
189
Nephron-sparing surgery for bilateral Wilms tumor.
Kathleen Kieran1, Andrew M Davidoff
1Division of Pediatric Urology, Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, RCP 3238, Iowa City, IA, 52242-1089, USA, kathleen-kieran@uiowa.edu.
Pediatric Surgery International
|January 31, 2015
Summary
Nephron-sparing surgery (NSS) can preserve kidney function in children with synchronous bilateral Wilms tumor (BWT). Outcomes are generally good with proper patient selection and treatment, highlighting NSS as a viable option for BWT.
Area of Science:
- Pediatric Oncology
- Nephrology
- Surgical Oncology
Background:
- Synchronous bilateral Wilms tumor (BWT) affects about 5% of children with Wilms tumor.
- BWT is linked to a higher risk of renal insufficiency.
- Nephron-sparing surgery (NSS) aims to preserve renal mass and function.
Purpose of the Study:
- To review the use of NSS in pediatric patients with BWT.
- To discuss oncologic and functional outcomes of NSS for BWT.
- To highlight key considerations for NSS in BWT management.
Main Methods:
- Literature review of published outcomes for NSS in BWT.
- Analysis of factors contributing to successful NSS outcomes.
- Discussion of patient selection and therapeutic strategies.
Main Results:
- Published oncologic outcomes for NSS in BWT are generally favorable.
- Functional outcomes demonstrate improved renal function with NSS.
- Successful outcomes are attributed to careful patient selection and surgical technique.
Conclusions:
- NSS is an effective approach for managing BWT.
- Preservation of renal function is a key benefit of NSS in BWT.
- Optimal patient selection and adjuvant therapies are crucial for successful BWT treatment with NSS.
Related Concept Videos
01:26Kidney Transplant II: Surgical Procedure
872
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
872
01:28Kidney Transplant I: Introduction
782
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
782
01:16Kidney Transplant III: Nursing Management
603
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
603
01:25Urinary Tract Calculi VI: Surgical Management
941
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
941